|
Chimerism Analysis
GenoProof®2 offers functionalities for chimerism analysis. Chimerism analyses are conducted to investigate the success of a bone marrow transplantation.
Shortly after transplantation, the patient will have both cells with the original genotype of the patient and cells with the genotype of the donator. The patient exhibits the characteristics of a chimera. In an ideal case, the fraction of cell with the original patient's genotype will reduce to zero within time, so that finally one finds only cell having the donator's genotype.
A chimerism analysis determines the ratio of both genotypes within a sample. The analysis can then be performed on either basis of peak areas or peak heights.
|
|
|
